The lead character in Galveston Ultra HD is Roy Cady. He is an assistant to an influential mobster. For his boss Roy performs various tasks and gets a good reward for it. One day the main character gets a new assignment from his boss. He has to sneak into a competitor's house unarmed and scare him. Roy goes on this criminal case with his partner. None of the men took the gun, which turns out to be a fatal mistake, because in the house they are attacked by armed persons. Roy's comrade is killed, and he manages to escape. Being able to fight back the attackers, the protagonist discovers a connected girl in the house. She is a prostitute named Raquel. She's unlucky to be in this house at such a bad time. Realizing that the ambush is organized by his boss, Roy decides to flee the city and offers his new friend to go with him. It's the only chance for the prisoner to stay alive, because the bandits will probably get to her too. The prostitute agrees to go with her savior, but before that she comes home to take her little sister on a journey...