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In "Teenage Mutant Ninja Turtles: Mutant Mayhem," the legendary quartet—Leonardo, Michelangelo, Donatello, and Raphael—leap back into action. This time, their archenemy, the Shredder, forms an unholy alliance with a sinister scientist, unleashing a wave of chaos upon the city. With the help of their fearless comrades April O'Neil and Casey Jones, the turtles embark on a perilous quest to thwart mutated adversaries and overcome treacherous obstacles, all in a bid to rescue New York from impending doom. Filled with martial arts, witty banter, and a shared love for pizza, the beloved turtles dive headfirst into a mutant-filled mayhem to safeguard the city's tranquility.