The protagonist of Rampage 4k dvd works in the reserve, where he has only one real friend. This is charming and smart gorilla male named George. The main character saved this animal many years ago, when George was very small. Friends haven't separated since then. Over the years, the primatologist has managed to bring up his unusual friend in such a way that the surrounding people only have to wonder about the abilities of this gorilla. It is enough to spend a few hours in the company of these two to make sure that they are real friends who understand each other with just one gesture. But the idyll collapses when the genetic experiment of a major biological corporation gets out of control. A space station explodes, bringing a dangerous mutagen to Earth that can change the structure of any animal organism. Unfortunately for the main character, George becomes one of the mutants. In a few days, the primate increases in size and becomes aggressive. Several other animals are also mutated. The owners of the corporation are going to use all such creatures for their own insidious purposes. Now, the main character's only mission is to save his mutated friend, who is now a threat to millions people.